| abstract |
The invention relates to the field of pharmaceuticals, namely, provides substituted 3-azabicyclo [3.1.0] hexanes as ketohexokinase inhibitors, methods for preparing said compounds and methods involving administering said compounds to a mammal in need thereof. The present invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein Y, Z, X, R, R, and R are as defined herein, pharmaceutical compositions based on them, and methods of treating a disease for which a KHK inhibitor is indicated. |