http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-035278-B1

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filingDate 2017-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9377c0728eb424ad1016bb52cd265cb
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publicationDate 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EA-035278-B1
titleOfInvention METHOD FOR PRODUCING TAMERIT AND / OR GALAVIT STERILE LYOPHYLIZED MEDICINE BASED ON 5-AMIN-2,3-DIHYDROPHTHALAZINE-1,4-DIUMORIUM SODIUM SULFUM AND TODIUM SODIUM 2,3-DIHYDROFTALAZINE-1,4-DIONE (GALAVIT)
abstract The invention relates to medicine, namely to medicines affecting the immune system and having immunomodulatory, anti-inflammatory, antitumor and antioxidant effects, as well as to the chemical and pharmaceutical production of these drugs. A method for producing a sterile lyophilized drug based on the sodium salt of 5-amino-2,3-dihydrophthalazine-1,4-dione by processing anhydrous and / or two-water non-sterile substance of the sodium salt of 5-amino-2,3-dihydrophthalazine-1,4 -dione, which is characterized in that they realize the process of processing the intermediate product of 5-amino-2,3-dihydrophthalazine-1,4-dione into its sodium salt by dissolving in an aqueous-organic alkaline solution so that an anhydrous and / or two-aqueous substance of sodium salts of 5-amino-2,3-dihydrophthalazine-1,4-dione are obtained by crystallization at a temperature of minus 5-7 ° C from an aqueous-organic solution of the sodium salt of 5-amino-2,3-dihydrophthalazine-1,4-dione, after which from the substance receive a sterile lyophilized drug.
priorityDate 2016-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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