| abstract |
The invention provides synthesis, pharmaceutically acceptable drugs and the use of compounds according to formula I, or their stereoisomers, tautomers or their pharmaceutically acceptable soligda in compounds of formula IA, A, A, A, A, A, A, W, R, R, R , R, R, R, R, R, R, R, R, R, R, R, R, R, R and the indices "m" and "n" are as defined herein. The compounds of formula I of the present invention are Mnk inhibitors and are useful in a variety of therapeutic applications, including but not limited to treating inflammation and various types of cancer. |