| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_064b250ffbc998ad3212d613aae43278 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1098 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
| filingDate |
2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb01536a53e666e5539aca24df2f8c28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_933de4b68e7d1a33d5cac8c4a3f7db6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cbffdd970c96ab9c980a2cadb38ee08 |
| publicationDate |
2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EA-034242-B1 |
| titleOfInvention |
METHOD FOR INDUCING TUMOR SIZE REDUCTION IN A HUMAN SUBJECT WITH CANCER |
| abstract |
The invention relates to a method for inducing a human subject having cancer, (i) destroying more than 70% of the cancer cells in the tumor volume (Vt) or (ii) reducing the tumor size by more than 20%, wherein said method comprises the step of administering to said subject a composition having a volume (Vc), wherein the composition contains inorganic nanoparticles having a volume (Vin), wherein said volume (Vin) has an electron density of at least 5 times the electron density of the corresponding volume 1 (Vw1) of water; and the step of exposing the tumor to said subject to ionizing radiation, thereby inducing in the human subject having cancer, (i) destruction of more than 70% of the cancer cells in the tumor volume (Vt) or (ii) reduction of the tumor size by more than 20%, where the volume (Vc) of the composition occupies between 2 and 15% of the tumor volume (Vt), and inorganic nanoparticles provide more than 7 × 10 electrons per tumor mass. The invention provides an unexpectedly effective therapeutic effect in the concentration of nanoparticles inside a tumor and exposing them to ionizing radiation. |
| priorityDate |
2013-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |