abstract |
The invention relates to compounds of the formula and their pharmaceutically acceptable salts, which possess the activity of modulators of the retinoid-related orphan gamma t receptor (RORγt). These compounds prevent, inhibit or suppress the action of RORγt and are thus suitable for the treatment of diseases, disorders, syndromes or conditions mediated by RORγt, such as, for example, pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis , neurodegenerative diseases and cancer. |