| abstract |
The invention relates to new benzodiazepine derivatives having antiproliferative activity, and more particularly to new benzodiazepine compounds of the formulas (I), (II) and (V). The invention also provides conjugates of benzodiazepine compounds attached to a cell-binding agent. In addition, the invention provides compositions and methods suitable for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention. |