| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44031669c54ba43c5dfba19f815933b5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40a7a0cd97f28fd756b5101179ff00a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_837899d9161ffe6ee6d723261a0955f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd691b17547ec1e42f4512e793cf78a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b890b19dbf11c1a94ff0d39fcb9d73d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60778a5f508d0bde60af0a573bd882bd |
| publicationDate |
2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EA-034088-B1 |
| titleOfInvention |
R2R1 / 2 GENE FOR TREATMENT AND DIAGNOSTICS OF CARDIAC AND PULMONARY DISEASES OR CONDITIONS, AS WELL AS CANCER |
| abstract |
The invention relates to the use of a polynucleotide containing a regenerative gene for respiratory R2R cells; the use of a protein encoded by the R2R gene; the use of an antisense oligonucleotide capable of modulating the expression of the R2R gene; the use of an antibody or antigen binding fragment thereof capable of binding to a protein encoded by the R2R gene and to the corresponding pharmaceutical compositions for the treatment of cardiac and pulmonary diseases or conditions, as well as cancer. In addition, the invention relates to a method for the diagnosis of these diseases or conditions, based on the detection of the level of expression of the R2R gene, and a method of testing the compound for its ability to modulate the expression of the R2R gene. The invention also relates to an animal model for the study of cardiac and pulmonary diseases or conditions, as well as cancer. |
| priorityDate |
2011-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |