| abstract |
Enhanced anti-HPV immunogens and nucleic acid molecules that encode them are disclosed. Disclosed immunogens include consensus HPV 6 E6E7, HPV 11 E6E7, HPV 16 E6E7, HPV 18 E6E7, HPV 31 E6E7, HPV 33 E6E7, HPV 39 E6E7, HPV 45 E6E7, HPV 52 E6E7 and HPV 52 E6E7 and HPV 58 E6E7. Disclosed are a pharmaceutical composition, recombinant vaccines containing a DNA plasmid, and live attenuated vaccines, and methods for stimulating an immune response in an individual against HPV are disclosed. |