abstract |
The compound of formula (I) where X, Y, R and R-R are as defined herein and its salts are PAD4 inhibitors and can be used in the treatment of various diseases, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer , cystic fibrosis, asthma, cutaneous form of lupus erythematosus and psoriasis. |