| abstract |
The invention relates to compounds of formula (I) and their salts, where R, R, R, R are as defined herein. It was found that the compounds of formula (I) and their salts inhibit the binding of the BET family of bromodomain proteins, for example, to acetylated lysine residues and, thus, can be used in therapy, for example in the treatment of autoimmune and inflammatory diseases, such as rheumatoid arthritis, and cancer diseases. |