| abstract |
The invention relates to an oral disintegrating film containing an active ingredient and a stabilizer, wherein the active ingredient is desmopressin or a pharmaceutically acceptable salt thereof and the stabilizer is at least one gum selected from galactomannan gum, which is selected from Arabian gum, bean gum carob gum, packaging gum and guar gum, carrageenan gum, xanthan gum, tragacanth gum, agar, quince seed gum, karaya gum, gum arabic and gell new gum, wherein the weight ratio of desmopressin, or a pharmaceutically acceptable salt, and gums (s) is in the range from 3: 1 to 1:10. In addition, the use of one or more of the above gums to increase the stability of the film disintegrating in the oral cavity is proposed. Also described is a method of producing a film disintegrating in the oral cavity. |