| abstract |
The invention relates to antibodies against FcRn and their fragments, to isolated DNA sequences encoding these antibodies and their fragments, to an expression and cloning vector, to a host cell for producing said antibodies, to a pharmaceutical composition containing said antibodies, to the use of antibodies and composition for the treatment of conditions associated with pathogenic IgG autoantibodies, such as myasthenia gravis, pemphigus vulgaris, opticoneuromyelitis, Guillain-Barré syndrome, lupus, idiopathic thrombocytopenic purpura RA and thrombotic thrombocytopenic purpura. |