abstract |
In the invention, compounds having a structure or their salts are used to treat or reduce the likelihood of acquiring androgen-dependent diseases such as prostate cancer, benign prostatic hyperplasia, polycystic ovary syndrome, acne, hirsutism, seborrhea, androgenic alopecia, male pattern baldness, muscular atrophy and weakness, sarcopenia, male hypogonadism, erectile dysfunction, female sexual dysfunction and osteoporosis. They may be formulated with a pharmaceutically acceptable diluent or carrier, or otherwise in any pharmaceutical dosage form. Possible combinations with other active pharmaceutical agents are also disclosed. |