| abstract |
The invention describes a monoclonal antibody or antigen-binding fragments thereof that bind to the AβpGlu (11) peptides, hybridoma cell lines that produce this antibody or its fragments, containing their pharmaceutical compositions. In addition, the application materials disclose the use of this monoclonal antibody and its fragments for diagnosing amyloidosis, in particular Alzheimer's disease, and related conditions, as well as for treating, preventing or slowing the development of amyloidosis, as well as the corresponding methods and kits used in them. |