abstract |
The invention relates to compounds that are inhibitors of Syk, and to their use for the treatment of various disease states, including cancer and inflammatory conditions. According to specific embodiments, the structure of the compounds is represented by formula (II) where R, R, R, R, R, and Y are as described herein. The present invention also provides pharmaceutical compositions that include a compound of formula (II) or pharmaceutically acceptable salts thereof, and methods of using said compounds and compositions for treating conditions mediated by Syk. |