http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-030904-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e2ce438cadc537d380bdf7eb344cb11 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 |
| filingDate | 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ed75c5978b146aa60222568bcbaaede http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_491100a9821bb64a68f8720993fb207c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccd24eec86a78cf26f27842ae86c77e1 |
| publicationDate | 2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-030904-B1 |
| titleOfInvention | A method for the treatment of ischemic lesions of the liver during its resection |
| abstract | The invention relates to medicine, namely to experimental surgery, and can be used for the treatment, correction and prevention of the effects of ischemic effects on the liver in the conditions of its temporary shutdown from the circulation. The technical result of the invention is the treatment, correction and prevention of ischemic and reperfusion injuries of the liver that occur during organ resection under conditions of temporary shutdown from the circulation, prolonging safe periods of bleeding the liver and, as a result, preventing massive bleeding during operations on it. For this experimental liver resection is performed, including clamping of the hepatoduodenal ligament, serotonin adipinate is administered: during the operation, into the hepatoduodenal ligament before it is clamped and immediately after its release at 0.2 mg / kg of weight into 5.0 ml infusion solution of mafusol jet slowly, then after surgery - on this day in the catheter placed in the hepatoduodenal ligament, at a dose of 0.5 mg / kg of weight per 75.0 ml of the infusion solution of mafusol at a rate of 30 drops per minute per 16 and 20, and on the second and third days - at 8, 12, 16 and 20, after which, at the end of the third day, the catheter is removed from the abdominal cavity and from the fourth to the ninth day, serotonin adipinate is administered intravenously, intravenously, slowly in 8 doses of 0.4 mg / kg of weight per 5.0 ml of mafusol infusion solution, additionally carry out slow intravenous injection once a day, starting from the day of surgery for nine days: Heptral in the form of injection solution at a dose of 10 mg / kg of weight in 10, mexicor as 5% solution in a dose of 10 mg / kg body weight at 14, clarithromycin in 10.0 m l of mafusol infusion solution at a dose of 10 mg / kg body weight in 18. |
| priorityDate | 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.