http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-029942-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b97d4f6f618c15f9ce7dd420b4cb135b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate | 2014-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4886f7790d041d4bcf25ce2d2e4a3d2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08f8b263c1840573b6dc000c7bace6f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c5853994f092be422345f02011ed637 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f729a522445e6b8ba38dacb3d9afe81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e1ef11235d099c027e3b55158418c45 |
| publicationDate | 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-029942-B1 |
| titleOfInvention | STABLE PHARMACEUTICAL COMPOSITION BASED ON CONJUGATES OF BIOLOGICALLY ACTIVE PROTEINS WITH POLYETHYLENE GLYCOL CONTAINING AZOGROUPE |
| abstract | The invention relates to the field of medicine and the pharmaceutical industry and provides a pharmaceutical composition presented in a liquid or lyophilized finished dosage form containing a pegylated protein corresponding to formula (I), in which polyethylene glycol fragments are covalently attached to the protein molecule by azo groups: where Prot is a biologically active protein ; A - amino acid fragment of histidine; B - amino acid fragment of tyrosine; n is an integer in the range from 10 to 1200; m is an integer in the range from 0 to 10; k is an integer ranging from 0 to 10, with m ≠ k, if m or k is 0, in the form of a conjugate or mixture of conjugates with different values of n, m and k, as well as pharmacologically acceptable auxiliary ingredients selected from cosolvents, salts , acids, bases, antioxidants, preservatives, amino acids, proteins, carbohydrates, polymers, detergents and complexones. The technical result consists in expanding the Arsenal of drugs. |
| priorityDate | 2014-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 291.