| abstract |
Problem. The aim of the present invention is to provide an anti-human CTGF antibody having excellent binding activity and / or neutralizing activity as compared to conventional anti-human CTGF antibodies, as well as a method for preventing or treating various diseases whose pathogenesis involves human CTGF, including kidney disease, such as chronic renal failure and diabetic nephropathy, using antibodies against human CTGF. Ways to solve the problem. Antibody against human CTGF contains the variable region of the heavy chain, consisting of the amino acid sequence of SEQ ID NO: 10; and the variable region of the light chain consisting of the amino acid sequence of SEQ ID NO: 4. |