abstract |
The invention relates to solid dosage forms for oral administration containing methylnaltrexone or a pharmaceutically acceptable salt thereof and an amphiphilic pharmaceutically acceptable excipient comprising a saturated or unsaturated, branched or unbranched, cyclic or acyclic aliphatic group C, which is optionally substituted, or saturated unsubstituted cyclic an alkyl group C. The present invention also relates to a method for preparing said dosage form and a method for reducing one or more side effects of opioid therapy in a subject being treated with opioids. |