http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-028946-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 |
| filingDate | 2012-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abb0e8c666c28a4e789d5afad59480f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb440cf3bc5b9918f2cb9f89edaf27cc |
| publicationDate | 2018-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-028946-B1 |
| titleOfInvention | METHOD OF OBTAINING COMPOUNDS FOR APPLICATION AS SGLT2 INHIBITORS |
| abstract | The invention relates to a new process for the preparation of compounds of formula (IA ') where the substituents R and C have the meanings indicated in the claims, and their pharmaceutically acceptable salts and solvates; containing the interaction of the compounds of formula (V), where LG represents a leaving group, with a mixture of zinc salts and organolithium reagent; in a hydrocarbon solvent; at a temperature in the range of from about -78 ° C to about room temperature; to prepare a mixture of the corresponding compound of formula (VI), where M is lithium, and zinc salts; mixing to the mixture a compound of formula (VI) and a zinc salt of an ether solvent; to obtain the corresponding compounds of formula (VII), where M is a reactive zinc particle. |
| priorityDate | 2011-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 244.