abstract |
Some condensed tetra- or pentacyclic compounds of general formula (II) or (III) are proposed, where the values Z, R, R, R, Y, n, p and p "are defined in the claims, or their pharmaceutically acceptable salts, which can inhibit poly (ADP-ribose) polymerase (PARP), pharmaceutical compositions containing at least one of these compounds, and their use in the treatment of malignant tumors that respond to PARP inhibition. |