| abstract |
HBV replication inhibitors of formula (I), including their stereochemical isomeric forms, as well as their salts, hydrates, solvates, where A – E, R, R, R and R have the values defined herein. The present invention also relates to methods for producing said compounds containing pharmaceutical compositions thereof, as well as to their use alone or in combination with other HBV inhibitors in therapy active against HBV. |