http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-026814-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b15870c9810f2d946ab8ecef85109d6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 2010-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1db886afb1f844d9d1b8f2bb383de7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cb2b508bdb2a64121afc0b48c0c070a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5352371acbaa3b8e4cd423ab5b32a80d |
| publicationDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-026814-B1 |
| titleOfInvention | APPLICATION OF A MODIFIED FRAGMENT OF AGRINE, THE CAPABLE TO RESTORE MUSCLE FORCE, TO MANUFACTURE THE MEDICINE |
| abstract | The invention relates to the use of a modified fragment of agrin, active in vivo and containing at least the domains LG2 and LG3 of human agrin or mouse in a covalently bonded form and containing between the indicated domains a modified β-cleavage site that cannot be cleaved by neurotrypsin, the specified fragment of agrin contains the amino acid sequence of SEQ ID NO: 3, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13 or SEQ ID NO: 14 for the manufacture of a medicine for the treatment of neurotrypsin-related diseases, in particular affecting muscle neuromuscular disease or diseases of the nerves, muscles and neuromuscular joints, such as muscle atrophy caused by inaction, or body depletion syndrome. |
| priorityDate | 2009-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.