abstract |
The proposed connection can be used as an agonist of the receptor MT1 and / or MT2. The inventors have conducted studies on MT1 and / or MT2 receptor agonists and have found that the indole-carboxamide compound has the action of an MT1 receptor and / or MT2 agonist, thus developing the present invention. The indole carboxamide compound of the present invention has the action of an MT1 and / or MT2 receptor agonist, as well as low permeability to CNS, and therefore, it can be used as an agent for the prevention and / or treatment of urological diseases; in one embodiment of the invention, symptoms of the lower urinary tract; in another embodiment of the invention, a symptom of urine retention, in another embodiment of the invention, urinary incontinence; in yet another embodiment of the invention, stress urinary incontinence and the like. |