http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-025222-B1

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filingDate 2010-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_870795a44b48d39dad91a77f5d3d9ad2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0975a663c6cc3a4361a43889ed643fa4
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publicationDate 2016-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EA-025222-B1
titleOfInvention COMPOUNDS AND COMPOSITIONS AS PROTEINKINAZ INHIBITORS
abstract The invention relates to compounds selected from the following compounds: N - [(2S) -1 - ({4- [3- (3-chloro-5-methanesulfonamidophenyl) -1- (propan-2-yl) -1H- methyl ester pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, methyl ester N - [(2S) -1 - [(4- {3- [3-chloro-5- (propane -1-sulfonamido) phenyl] -1- (propan-2-yl) -1H-pyrazol-4-yl} pyrimidin-2-yl) amino] propan-2-yl] carbamic acid, methyl ester N - [(2S ) -1 - ({4- [3- (3-chloro-2-methanesulfonamidopyridin-4-yl) -1- (propan-2-yl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino ) propan-2-yl] carbamic acid, methyl ester of N - [(2S) -1 - ({4- [3- (3-fluoro-2-methanesulfonam opyridine-4-yl) -1- (propan-2-yl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, methyl ester N - [(2S) -1 - ({4- [3- (2-chloro-3-ethanesulfonamido-4,5-difluorophenyl) -1- (propan-2-yl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, N - [(2S) -1 - ({4- [3- (2,4-difluoro-3-methanesulfonamidophenyl) -1- (propan-2-yl) methyl ester -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, methyl N - [(2S) -1 - ({4- [1- (propan-2-yl ) -3- (2,4,5-trifluoro-3-methanesulfonamidophenyl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, methyl ester N - [(2S ) - 1 - ({4- [3- (3-methanesulfonamidophenyl) -1- (propan-2-yl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, N - [(2S) -1 - [(4- {3- [2,4-difluoro-3- (propan-1-sulfonamido) phenyl] -1- (propan-2-yl) -1H-pyrazole methyl ester -4-yl} pyrimidin-2-yl) amino] propan-2-yl] carbamic acid, methyl ester N - [(2S) -1 - ({4- [3- (3-cyclopropanesulfonamido-2,5-difluorophenyl ) -1- (propan-2-yl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl] carbamic acid, methyl ester N - [(2S) -1 - ({ 4- [3- (5-chloro-3-cyclopropanesulfonamido-2-fluorophenyl) -1- (propan-2-yl) -1H-pyrazol-4-yl] pyrimidin-2-yl} amino) propan-2-yl ] carbamine acids, N - [(2S) -1 - [(4- {3- [5-chloro-2-fluoro-3- (propan-1-sulfonamido) phenyl] -1- (propan-2-yl) methyl ester -1H-pyrazol-4-yl} pyrimidine-2-yl) amino] propan-2-yl] carbamic acid, methyl ester
priorityDate 2009-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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