abstract |
Heteroaromatic compounds of the formula I: (I) are reverse transcriptase inhibitors, where R, R, R, R and R have the meanings specified in the description. The compounds of formula I and their pharmaceutically acceptable salts are useful in inhibiting HIV reverse transcriptase, preventing and treating infections caused by HIV, and in preventing, preventing the occurrence or development and in treating AIDS. The compounds and their salts can be used as ingredients in pharmaceutical compositions, optionally in combination with other antiviruses, immunomodulators, antibiotics or vaccines. |