| abstract |
The present invention describes a variant of Csy4 endoribonucleases, nucleic acids encoding a variant of Csy4 endoribonucleases, and host cells genetically modified with nucleic acids. The Csy4 variant of endoribonuclease finds various uses, which are also described. The present invention also describes methods for detecting a specific sequence in a target polyribonucleotide and methods for regulating the production of a target RNA in a eukaryotic cell. |