| abstract |
A compound is proposed that has an intestinal phosphate transporter inhibition action (NPT-IIb) and is useful as an active ingredient of an agent for treating and / or preventing hyperphosphatemia. The authors of the present invention conducted studies on compounds that have inhibitory NPT-IIb action and is applicable as an active ingredient of the agent for the treatment and / or prevention of hyperphosphatemia. As a result, they developed a derivative of an aminoalkyl-substituted N-thienylbenzamide of formula (I) in which all the substituents have the meanings disclosed in the claims, which has an inhibitory NPT-IIb effect, thereby completing the present invention. The aminoalkyl-substituted N-thienylbenzamide derivative of the present invention has inhibitory NPT-IIb action, and can be used as an agent for the prevention or treatment of hyperphosphatemia. |