| abstract |
The invention describes new pyrazolopyrimidinones of the formula (I) in which R5 represents a pyridyl or pyrimidinyl group, and D stands for an optionally substituted cyclopentyl, cyclohexyl, tetrahydrofuranyl, tetrahydropyranyl or 2-, 3- or 4-pyridyl. These new compounds are intended for use as an active component of drugs or for the preparation of drugs, respectively, preferably drugs for the treatment of pathological conditions associated with lack of perception, concentration, learning ability or memory. Such pathological conditions may be associated, for example, with Alzheimer's disease, schizophrenia and other diseases. These new compounds are also applicable, for example, for the preparation of drugs and / or for use in the treatment of these diseases, in particular the cognitive impairment associated with such a disease. The described compounds have the ability to inhibit PDE9. |