abstract |
The present invention relates to proteins based on the structural domain of fibronectin, which bind PCSK9. The invention also relates to the use of these innovative proteins in therapeutic applications for the treatment of atherosclerosis, hypercholesterinemia and other diseases associated with elevated cholesterol. This invention also relates to cells containing these proteins, polynucleotides encoding these proteins or fragments thereof, and vectors containing these polynucleotides encoding these innovative proteins. |