| abstract |
The invention relates to new derivatives of thienopyrimidinedione as TRPA (transient receptor potential in subfamily A) modulators. In particular, the compounds described herein are useful for the treatment or prevention of diseases, conditions and / or disorders modeled by TRPA1 (transient receptor potential of subfamily A, member 1). Also provided are methods for preparing the compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and / or disorders modulated by TRPA1. |