| abstract |
The invention relates to sulfonylpyrazoline derivatives of carboxamidine as antagonists of 5-HT receptors and new intermediates useful for their synthesis. The invention also relates to the use of such compounds and compositions, especially their use when administered to patients in order to achieve a therapeutic effect in Parkinson's disease, schizophrenia, anxiety, depression, psychoses, epilepsy, obsessive-compulsive disorders, Alzheimer's disease, age-related decrease in cognitive function, small cognitive impairment, sleep disorders, withdrawal of cocaine, ethanol or nicotine, pain and type 2 diabetes. The compounds have the general formula (1) where the symbols mean data in the description. |