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filingDate 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bd2f7eac1255c68ca28a0cfeb8f47c5
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publicationDate 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EA-021148-B1
titleOfInvention PIPE TABLETS FOR INHALATION USE
abstract The invention relates to an effervescent tablet for extemporaneous suspension preparation for inhalation administration, comprising at least one water-insoluble active ingredient, the initial particle size of which is from 0.5 to 7 microns, where the specified active ingredient is chosen from corticosteroids and mucolytic agents; an acidic compound selected from citric acid and tartaric acid; and a basic compound selected from carbonate, bicarbonate, thermally treated carbonate, and thermally treated bicarbonate; as well as non-ionic or ionic surfactant. The tablet is dissolved in the solution to obtain a fine suspension. The suspension retains the original distribution of drug particles in size, ensuring that the therapeutic window of the inhaled fraction is reached.
priorityDate 2007-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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