abstract |
The invention relates to a compound that exhibits the ability to inhibit PDE and which is suitable as a medicine for preventing or treating schizophrenia or the like. A compound of formula (I), wherein R-R is defined in the claims; ring A is a benzene ring which may be substituted; and ring B is a pyrazole ring which may be substituted, or a salt thereof. The invention also relates to a medicinal preparation containing a compound of formula (I) or its salt as a means for inhibiting phosphodiesterase 10A. The invention relates to the use of said compound or its salt in the manufacture of a medicament for the prevention or treatment of schizophrenia, autism, Alzheimer's disease, bipolar disorder, Parkinson's disease, Huntington's disease, obesity, drug addiction or attention deficit hyperactivity disorder and to the treatment and prevention of these diseases or states. |