| abstract |
The present invention relates to new derivatives of triazolo [4,3-a] pyridine of the formula (I), where all the radicals are as defined in the claims. The compounds of the invention are positive allosteric modulators of the metabotropic glutamate subtype 2 receptor (mGluR2), which are useful for treating or preventing neurological and psychiatric disorders associated with glutamate dysfunction and diseases involving the mGluR2 subtype of the metabotropic receptors. The invention also relates to pharmaceutical compositions containing such compounds, to methods for producing such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved. |