| titleOfInvention |
7 - ([1,2,4] TRIAZOLO [1,5-α] PYRIDIN-6-IL) -4- (3,4-DICHLOROPHENIL) -1,2,3,4-TETRAHYDRO-ISOHINOLINE, PHARMACEUTICAL COMPOSITION ON ITS BASIS AND METHODS OF TREATMENT OF NEUROLOGICAL AND MENTAL DISORDERS |
| abstract |
The invention relates to new [1,2,4] triazolo [1,5-α] pyridinyl-6-yl substituted by a derivative of tetrahydroisoquinolines of the formula (I) wherein the carbon atom indicated by * is in the R- or S-configuration; or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) or a salt or solvate thereof for the treatment of various neurological and mental disorders. The invention also relates to a method of treating a disorder that is caused or depends on a decrease in the availability of norepinephrine, dopamine or serotonin, to methods of inhibiting the reuptake of synaptic norepinephrine, serotonin or dopamine in a patient, to a method of suppressing people’s craving for smoking and to a method of suppressing people's desire to drinking alcohol, comprising administering a therapeutically effective amount of a compound of formula (I) or a salt or solvate thereof. |