http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-020526-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0597f9c318d2aeca86db94711c516383 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 |
filingDate | 2010-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff796148e25daac7b697321130094f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47e1c33131f6eb7dd329bfd1d3d14251 |
publicationDate | 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EA-020526-B1 |
titleOfInvention | APPLICATION N- (4 - ((3- (2-AMINO-4-PYRIMIDINYL) -2-PYRIDINIL) OXY) PHENYL)) -4- (4-METHYL-2-THIENYL) -1-PHTALASINAMINE FOR THE TREATMENT OF RESISTANT TO ANTIMYTOTCHOLOGY CANCER |
abstract | The invention relates to methods of using the compound N- (4 - ((3- (2-amino-4-pyrimidinyl) -2-pyridinyl) oxy) phenyl) -4- (4-methyl-2-thienyl) -1-phthalazinamine or its pharmaceutically acceptable salt for treating cancer, including solid tumors that have become resistant to treatment with chemotherapeutic agents, including antimitotic agents such as taxanes, and / or other anti-cancer agents, including Aurora kinase inhibiting agents. The invention also includes methods of treating cancer refractory to such therapies by administering a pharmaceutical composition containing the compound to a subject having cancer. |
priorityDate | 2009-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 181.