http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-020473-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-027 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-096 |
| filingDate | 2010-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8471d45fa9c1955864c3972769c6a753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6ae6e5c4f519a8d991306159c9ecfec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fecd6096aadb2d0dcccef4618d7721bf |
| publicationDate | 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-020473-B1 |
| titleOfInvention | METHOD OF CLEANING 1- [2- (2,4-DIMETHYLPHENYL SULPHANIL) PHENYL] PIPERAZINE-HBr |
| abstract | The invention relates to a method for the purification of 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine-HBr, comprising steps a) of obtaining a solution by dissolving 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine-HBr in a solvent, containing more than 65% (by volume) of isopropanol; b) precipitating 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine-HBr isopropanol solvate from the solution obtained above; c) dissolving the isopropanol solvate of 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine-HBr in a solvent that does not form a solvate; and d) precipitating 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine-HBr from the solution obtained in step c). The present invention also relates to a novel compound, which is the 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine-HBr isopropanol solvate, which is characterized by peaks of an x-ray powder diffraction pattern of approximately 6.44, 8.13, 8.77, 10 , 41 (° 2Θ) and has a X-ray powder diffraction pattern shown in FIG. 2 |
| priorityDate | 2009-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.