| abstract |
The invention relates to compounds corresponding to the formula (I), in which R represents -SO-NR3R4, hydrogen atom halogen atom -halo (C-C) alkyl, -COR5 or -SOR4; R1 is heterocycloalkyl, nitrogen free -W- (C-C) cycloalkyl, -W-aryl, -W-heteroaryl, -W-heterocycloalkyl, -W-COOR5, -W-CONR5R6; R2 represents a hydrogen atom, - (C-C) alkyl, - (C-C) alkylene-O- (C-C) alkyl, -halo (C-C) alkyl, -W-COOR5, -W-C (O) NHR5 or -W-C (O) NR5R6; n is 0, 1 or 2; W is - (C — C) alkylene - or - (C — C) cycloalkylene—; R3 and R4, being the same or different independently such groups are like a hydrogen atom - (C-C) alkyl, - (C-C) cycloalkyl, - (C-C) alkylene-O- (C-C) alkyl, aryl -CH-aryl, heteroaryl heterocycloalkyl, -W-OH, -W-CHOH-CHOH, -W-COR5, -W-NR5R6 or -W-O- (CH) -aryl; or R3 and R4 together with a nitrogen atom, with which they are associated form heterocycloalkyl; R5 and R6, being the same or different independently represent hydrogen atoms, - (C — C) alkyls or (C — C) haloalkyls; The invention also relates to a method for their preparation and their use in therapy. |