abstract |
The invention relates to antigen-binding proteins for IL-17 receptor A (IL-17RA, or IL-17R), such as antibodies, polynucleotide sequences encoding such antigen-binding proteins, and compositions and methods for diagnosing and treating diseases mediated by activation of IL-17 receptor A one or more IL-17 ligands. The invention relates to the identification of neutralizing determinants that compete for binding with antibodies neutralizing IL-17RA according to this description. |