| abstract |
The invention relates to modulating sirtuin compounds of the formula (II) and methods for their use. Sirtuin modulating compounds can be used to increase cell life and treat and / or prevent a wide range of diseases or disorders, including, for example, diseases and disorders associated with aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, coagulation disorders blood, inflammation, malignant diseases and / or hot flashes, as well as diseases or disorders in which positive mitochondrial activity will be exerted by a positive new action. Compositions containing a sirtuin modulating compound in combination with another drug are also provided. |