| abstract |
In accordance with the invention, a method for producing virus-like particles (HF) in a plant or part thereof is provided. The method includes introducing HA of influenza virus into plants and purification by size exclusion chromatography. The invention also provides RFs containing influenza virus HA protein and plant lipids. The invention also provides a nucleic acid encoding the influenza virus GA, as well as vectors. HF can be used to create influenza vaccines, or to improve existing vaccines. |