abstract |
The present invention relates to nucleic acid molecules containing a double-stranded region, and nucleic acid constructs encoding them that can be used to treat and / or prevent influenza. In particular, the present invention relates to nucleic acid constructs encoding a double-stranded RNA molecule (s) that can be used to produce transgenic poultry, such as chickens, so that they are at least less susceptible to bird flu infection. Nucleic acid molecules containing a double-stranded region that can be used as a therapeutic agent for the treatment and / or prophylaxis of, for example, bird flu in poultry are also presented. |