| abstract |
SUBSTANCE: invention relates to antagonists of serotonin 5-HT receptors - substituted 2-alkylsulfanyl-3-arylsulfonylcycloalkano [e and d] pyrazolo [1,5-a] pyrimidines of general formulas 1 and 2, new medicinal principles and pharmaceutical compositions containing medicinal principles in the form of the indicated compounds, as well as to new drugs and a method for treating and preventing the development of central nervous system diseases in humans and warm-blooded animals, the pathogenesis of which is associated with 5-HT receptors, R represents a hydrogen atom or C-C1-6 alkyl; R 1 is C 1-6 alkyl; R 1 represents a hydrogen atom, one or two optionally identical halogen atoms, C 1-6 alkyl or optionally substituted C 1-6 alkyl hydroxyl; n is an integer of 1, 2 or 3. |