| abstract |
The present invention relates to a new method for sulfinylation of a pyrazole derivative, characterized in that 5-amino-1- [2,6-dichloro-4- (trifluoromethyl) phenyl] -1H-pyrazole-3-carbonitrile (II) is reacted with a sulfinylating agent S in the presence of at least one amino / acid complex in which the amine (s) is (are) selected from secondary and / or tertiary amines and the acid (s) is (are) selected from fluoride hydrochloric, hydrochloric, hydrobromic and hydroiodic acids and derivatives of sulfones acid minutes, adding a halogenating agent, wherein S represents [CFS (O)] O or CFS (O) X, wherein X is fluoro, chloro, bromo, iodo, hydroxy, or a salt of an alkali or alkaline earth metal hydroxy; or mixtures thereof, where the temperature of the reaction mixture never exceeds 39 ° C. |