http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-014783-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb0e564374fedf34b36103d36e6455a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 |
| filingDate | 2006-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b0225807cdaea54046fdf2f7de8a614 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eee046058ed2befc22067f261c52ac9 |
| publicationDate | 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-014783-B1 |
| titleOfInvention | BINDING DNA SITE OF TRANSCRIPTION ACTIVATOR SUITABLE FOR GENE EXPRESSION |
| abstract | DNA binding sites that are specifically recognized by the PrtT protease gene transcription activator are described. A DNA binding site can be determined structurally by a consensus nucleotide sequence, as well as functionally, based on the ability of PrtT to regulate transcription activation through a given sequence. Both PrtT and its corresponding DNA-binding site (that is, the nucleotide sequence in each promoter that is recognized by PrtT) can be used in a gene expression system. The presence of only one PrtT transcription activator is insufficient, the corresponding DNA-binding site is necessary for PrtT recognition (i.e., site binding and transcription activation under suitable conditions). A functional site, such as a site derived from a wild-type fungus gene, will provide PrtT-dependent transcription activation from the 3 ′ downstream sequences. A mutation of a wild-type promoter that results in a non-functional site will disrupt the PrtT-dependent activation of transcription of the 3'-downstream sequences. Mutation of the wild-type promoter, which results in a more functional site, will enhance PrtT-dependent transcription activation from the 3'-downstream sequences. |
| priorityDate | 2005-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.