| abstract |
The invention describes novel benzimidazole derivatives, compositions and methods for inhibiting kinase activity associated with oncogenesis in humans or animals. In specific embodiments, the compounds and compositions are effective in inhibiting at least one serine / threonine kinase or tyrosine kinase receptor. New compounds and compositions can be used individually or in combination with at least one additional agent for the treatment of a mediated serine / threonine kinase or tyrosine kinase receptor disease, such as cancer. |