Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_995c71109762882f3cc26e74d8d61acf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5252 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
filingDate |
2006-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c44c138247da48485342c9daa3c0345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09bf360a061bac1cea106be819d9b622 |
publicationDate |
2010-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EA-014062-B1 |
titleOfInvention |
VIRAL VACCINES OBTAINED FROM CELLS WITH LOW LEVELS OF RESIDUAL CELL DNA |
abstract |
The present invention relates to vaccines for treating or preventing viral infections. In addition, methods for reducing the amount of contaminants associated with the production of cell culture vaccines are provided. The residual functional DNA of cell cultures is destroyed by treatment with a DNA alkylating agent such as β-propiolactone (BPL), thereby facilitating the preparation of a vaccine comprising immunogenic proteins derived from a virus propagated from a cell culture substantially free of residual functional DNA of the cell culture . |
priorityDate |
2005-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |