| abstract |
The invention relates to compounds of the general formula (I), in which X, X, X, Xo are independently H, F, CF, N (CH) or tBu; W means a group selected from benzimidazolyl, indolyl, quinolyl, tetrahydroquinolyl, benzothiazolyl or benzoxazinyl; moreover, these groups can be substituted 1 or 2 times by groups selected from (C-C) alkyl, C-C-cycloalkyl and oxo, which themselves can be substituted by C-C-cycloalkyl; n is 1, 2 or 3; Y represents a group selected from pyridyl, imidazolyl, benzimidazolyl, thiazolyl, quinolyl, isoquinolyl, furyl, quinoxalinyl, pyridazinyl, pyrazinyl or pyrimidinyl; moreover, these groups can be substituted 1 or 2 times by groups selected from (C-C) alkyl, (C-C) fluoroalkyl, benzyl, morpholinyl; in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate; in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate; the method of preparation and use in therapy. |