abstract |
A pharmaceutical composition comprising a pharmaceutical diluent and a compound of formula I, wherein R is H, C — C alkyl, cycloalkyl, alkenyl, aryl, arylalkyl or alkylaryl, —CHOR; —C (O) R, —CO (O) R, —C (O) NRR, —CHC (O) R, or —CHC (O) NHR, where each of R and R is independently H, CC-alkyl, cycloalkyl, alkenyl , aryl, arylalkyl or alkylaryl optionally containing one or more halogen atoms, R = —OH, —OR, —OCHC (O) R, —OCHC (O) NHR, —OC (O) R, —OC (O) OR , —OC (O) NHNH — R or —OC (O) NRR, where each of R and R is independently H, CC-alkyl, cycloalkyl, alkenyl, aryl, arylalkyl or alkylaryl, and each of R and R may optionally contain halogen atoms; R and R are the same or different from each other and are C-Calkyl, cycloalkyl, alkenyl, aryl, arylalkyl or alkylaryl. Also disclosed are methods of using such compositions for treating cancer, losing weight, treating infections caused by microbes, for inhibiting neuropeptide-Y and / or synthase of fatty acids, and for stimulating CPT-1. |